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dc.contributor.authorBezerra, Taliana; et. al.-
dc.contributor.otherPT_Br
dc.date.accessioned-
dc.date.accessioned2021-07-12T19:36:30Z-
dc.date.availablePT_Br
dc.date.available2021-07-12T19:36:30Z-
dc.date.copyright-
dc.date.issued2020-
dc.identifierPT_Br
dc.identifier.citationBEZERRA, T. K. A. et. al. Chicken combs and wattles as sources of bioactive peptides: optimization of hydrolysis, identification by LC-ESI-MS2 and bioactivity assessment. MOLECULES, v. 25, p. 1-25, 2020.pt_BR
dc.identifier.urihttp://repositorio.ital.sp.gov.br/jspui/handle/123456789/141-
dc.description.abstractThe production of bioactive peptides from organic by-waste materials is in line with current trends devoted to guaranteeing environmental protection and a circular economy. The objectives of this study were i) to optimize the conditions for obtaining bioactive hydrolysates from chicken combs and wattles using Alcalase, ii) to identify the resulting peptides using LC-ESI-MS2 and iii) to evaluate their chelating and antioxidant activities. The hydrolysate obtained using a ratio of enzyme to substrate of 5% (w/w) and 240 min of hydrolysis showed excellent Fe2+ chelating and antioxidant capacities, reducing Fe3+ and inhibiting 2, 20-Azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. The mapping of ion distribution showed that a high degree of hydrolysis led to the production of peptides with m/z 400, suggesting low mass peptides or peptides with multiple charge precursor ions. The peptides derived from the proteins of cartilage like Collagen alpha-2(I), Collagen alpha-1(I), Collagen alpha-1(III) and elastin contributed to generation of bioactive compounds. Hydrolysates from chicken waste materials could be regarded as candidates to be used as ingredients to design processed foods with functional properties.pt_BR
dc.description.sponsorshipCNPq / CAPESpt_BR
dc.formatPT_Br
dc.languagePT_Br
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dc.rightsPT_Br
dc.sourcePT_Br
dc.subjectProtein hydrolysatept_BR
dc.subjectFree radicalspt_BR
dc.subjectChicken by-productspt_BR
dc.subjectBioactive compoundspt_BR
dc.subjectLC-ESI-MS2pt_BR
dc.titleChicken Combs and Wattles as Sources of Bioactive Peptides: Optimization of Hydrolysis, Identification by LC-ESI-MS2 and Bioactivity Assessmentpt_BR
dc.typeArticlept_BR
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