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dc.contributor.authorSilva, Maria Elisa Caetano; et. al.-
dc.contributor.otherPT_Br
dc.date.accessioned-
dc.date.accessioned2021-10-27T18:19:35Z-
dc.date.availablePT_Br
dc.date.available2021-10-27T18:19:35Z-
dc.date.copyright-
dc.date.issued2020-
dc.identifierPT_Br
dc.identifier.citationCritical Reviews in Food Science and Nutrition, v. 5, p. 1-20, 2020. https://doi.org/10.1080/10408398.2020.1761770pt_BR
dc.identifier.urihttp://repositorio.ital.sp.gov.br/jspui/handle/123456789/184-
dc.description.abstractBioactive peptides derived from food protein sources have been widely studied in the last years, and scientific researchers have been proving their role in human health, beyond their nutritional value. Several bioactivities have been attributed to these peptides, such as immunomodulatory, antimicrobial, antioxidant, antihypertensive, and opioid. Among them, metal-binding capacity has gained prominence. Mineral chelating peptides have shown potential to be applied in food products so as to decrease mineral deficiencies since peptide-metal complexes could enhance their bioavailability. Furthermore, many studies have been investigating their potential to decrease the Fe pro-oxidant effect by forming a stable structure with the metal and avoiding its interaction with other food constituents. These complexes can be formed during gastrointestinal digestion or can be synthesized prior to intake, with the aim to protect the mineral through the gastrointestinal tract. This review addresses: (i) the amino acid residues for metal-binding peptides and their main protein sources, (ii) peptide-metal complexation prior to or during gastrointestinal digestion, (iii) the function of metal (especially Fe, Ca, and Zn)-binding peptides on the metal bioavailability and (iv) their reactivity and possible pro-oxidant and side effects.pt_BR
dc.description.sponsorshipFAPESPpt_BR
dc.formatPT_Br
dc.languagePT_Br
dc.language.isoenpt_BR
dc.publisherTaylor & Francispt_BR
dc.rightsPT_Br
dc.sourcePT_Br
dc.subjectMetal-binding peptidespt_BR
dc.subjectBioavailabilitypt_BR
dc.subjectMineral deficiencypt_BR
dc.subjectBioactive peptidespt_BR
dc.subjectHydrolysatespt_BR
dc.subjectMetal-peptide complexespt_BR
dc.titlePeptide-metal complexes: obtention and role in increasing bioavailability and decreasing the pro-oxidant effect of mineralspt_BR
dc.typeArticlept_BR
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